What version of the APC software are you currently running? What OS (I assume a version of Windows) is the software running on? Have you checked the device manager to see if there is an ! under any of your Hhuman Interface Device (HID)/USB device names/listings?
When you hover over the toolbar icon, is there a pop-up summary of what the issue is?
Can you take a few screenshots of each page of the software and attach them here to the thread so that we can look and see if anything seems out of place? Thanks.
Running Vista, Power Chute Personal Ed. 2.1.1. Same problem--reinstall did not help. I takes about 10 minutes before the APC UPS service stops running. Is this some administrator privilege problem perhaps?